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RADIATION

Medical and industrial uses of radioactive materials

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America's advanced industrial economy and high standard of living would not be possible without the use of radioactive materials. They make it possible to do many jobs better, easier, quicker, cheaper and more simply. In some cases, there are no alternatives to radioactive materials.

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Radioactive materials are used extensively in medical diagnosis and treatment; research into cures for disease; the development of new drugs; hardier, more disease-resistant crops; everyday consumer goods and services; and the nuclear energy that supplies about one-fifth of our electricity—to name just a few.

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Radioactive materials also provide substantial economic and employment benefits to Americans. Every year, radioactive materials—not counting those related to the generation of electricity—are responsible for approximately $330.7 billion in total industry sales; four million jobs; and $60 billion in tax revenues to local, state and federal governments. The direct and indirect economic impact of nuclear energy for generating electricity totals $90 billion in total sales of goods and services; 442,000 jobs; and $17.8 billion in federal, state and local government tax revenues.

Where do radioactive materials come from?
Some radioactive elements, such as radium, are found in nature, but most radioactive materials are produced commercially in nuclear reactors or cyclotrons—also called particle accelerators. A cyclotron uses electric current to accelerate atomic particles, which strike the non-radioactive "target" material, turning it into a radioactive isotope—or variant—of its original structure.

For example, when the non-radioactive "target" element cobalt is struck by neutrons in a reactor, it is transformed into a radioisotope—cobalt-60—which is used to treat cancer and sterilize medical and consumer products.

Usually only one type of radionuclide can be produced at a time in a cyclotron, while a reactor can produce many different radionuclides simultaneously. With nuclear reactors and cyclotrons, it is possible to make useful amounts of radioactive material safely and at low cost.

Once radionuclides are produced, they are packaged and safely shipped to users throughout the country, including hospitals, laboratories, universities and manufacturing plants.

Companies that produce and sell radioactive materials are licensed and inspected by the Nuclear Regulatory Commission or the state regulatory agency, and—if the product is a pharmaceutical—by other agencies, including the Food and Drug Administration.

How radioactive materials are used
Medicine—Every year, one in three of the 30 million Americans who are hospitalized are diagnosed or treated with nuclear medicine techniques. Radionuclides are used in more than 11 million nuclear medicine procedures every year in the United States. They also are used in 100 million laboratory tests on body fluid and tissue specimens.

Diagnosis is one of the main uses of nuclear medicine. It is made possible by the tendency of some natural elements to concentrate in certain parts of the body: iodine in the thyroid, phosphorus in the bones, potassium in the muscles. When a patient is injected with a radioactive element, a special camera can take pictures of the internal workings of the organ. For example:

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Myocardial perfusion imaging maps the blood flow to the heart, allowing physicians to see whether a patient has heart disease and determine what kind of treatment will be most effective.

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Bone scans can detect the spread of cancer six to 18 months sooner than X-rays.

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Kidney scans are much more sensitive than X-rays or ultrasound in fully evaluating kidney function.

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Imaging with radioactive technetium-99m can help diagnose bone infections in young children at the earliest possible stage.

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Laboratory techniques using radioactivity can detect underactive thyroids in newborn babies, making prompt treatment possible and saving many children from mental retardation.

Radionuclides—in a stronger form—also can be used to treat disease. When President and Mrs. Bush suffered from Graves' disease, a thyroid condition, they were cured by drinking a form of radioactive iodine that concentrates naturally in the thyroid and destroys the diseased portion. This treatment is so successful that it has virtually replaced thyroid surgery.

Radioactive iodine is also widely used to treat thyroid cancer. Compared to drug therapy, it has a lower recurrence rate and avoids potentially fatal side effects like destruction of bone marrow.

Scientific research—The Food and Drug Administration requires all new drugs to be tested for safety and effectiveness. More than 80 percent of those drugs are tested with radioactive materials.

Radioactive materials also are essential to the biomedical research that seeks causes and cures for diseases like AIDS, cancer and Alzheimer's disease.

Radionuclides are used extensively in metabolic studies, genetic engineering and environmental protection studies.

Carbon-14, a naturally occurring, long-lived radioactive substance, makes it possible for archaeologists to tell when artifacts containing plant or animal material were alive, created or used. For example, carbon-14 dating showed that the Shroud of Turin did not belong to the period when Christ was alive.

Criminal investigators use radiation to examine physical evidence and to link suspects to crimes. Museums rely on radioactive materials to verify the authenticity of paintings and art objects.

Industry—Today, practically every industry uses radioactive materials. Because radiation loses energy as it passes through substances, industry has been able to develop highly sensitive gauges to measure the thickness and density of many materials, as well as imaging devices to inspect finished goods for weaknesses and flaws.

Small amounts of a radioactive substance are commonly used as tracers in process materials. They make it possible to track leakage from piping systems, monitor the rate of engine wear and corrosion of processing equipment, observe the velocity of materials through pipes and gauge system filtration efficiency.

Radiation detection instruments are widely used, because they make it possible to take measurements without direct physical contact with the substance being measured, and they provide excellent cost savings. For example, level gauges containing radioactive sources are used where heat, pressure or corrosive substances, like molten glass or metal, make it difficult or impossible to use direct contact gauges.

Other industrial uses of radioactive materials:
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The automobile industry uses radioactive materials to test the quality of steel in cars.

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Aircraft manufacturers use radiation to check for flaws in jet engines.

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Mining and petroleum companies use radionuclides to locate and quantify mineral deposits.

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Can manufacturers use radioactive materials to obtain the proper thickness of tin and aluminum

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Pipeline companies use radioactive materials to look for defects in welds.

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Oil, gas and mining companies use radioactive materials to map geological contours, using test wells and mine bores, and to determine the presence of hydrocarbons.

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Construction crews use radioactive materials to gauge the density of road surfaces and subsurfaces.

Agriculture—Radionuclides are a basic tool for agricultural scientists around the world. Among their many uses: 

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Hundreds of new varieties of hardier, more disease-resistant crops—including peanuts, tomatoes, onions, rice, soybeans and barley—have been developed in agricultural research laboratories through the use of radioactive materials.

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Radioactive materials have been used to improve the nutritional value of some crops, as well as improve their baking or melting qualities or reduce their cooking time.

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To breed disease-resistant livestock, scientists use radioactive material to pinpoint where illnesses strike animals.

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By showing how plants absorb fertilizer, radioactive materials help researchers learn when fertilizer should be applied and how much is needed. This helps prevent the overuse of fertilizers, a major source of soil and water pollution.

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Radioactive materials help farmers and scientists control insect pests. Unlike chemicals, which can leave unhealthful residues in the soil, on plants and in water, this technology does not pollute. California has used radiation sterilization techniques since the mid-1970s to control infestations of Mediterranean fruit flies.

Consumer products and services—Radioactive materials supply necessities and conveniences that virtually everyone depends on.

n More than 100 nuclear power plants provide about one-fifth of U.S. electricity. Vermont, New Jersey, New Hampshire and South Carolina generate more than 50 percent of their electricity from nuclear energy.
n Many smoke detectors—installed in nearly 90 percent of U.S. homes—rely on a tiny radioactive source to sound the alarm when it senses smoke from a fire.
n Computer disks "remember" data better—when they are treated with radioactive materials.
n Nonstick pans are treated with radiation to ensure that the coating will stick to the surface.
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Photocopiers use small amounts of radiation to eliminate static and prevent paper from sticking together and jamming the machine.

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Cosmetics, hair products and contact lens solutions are sterilized with radiation to remove irritants and allergens.

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Radioactive materials also are used to sterilize medical bandages and a variety of personal health and hygiene products.

Economic and employment benefits of radioactive materials
Each year in the United States, radioactive materials—not counting those involved in the operation of nuclear power plants-are directly and indirectly responsible for about $330.7 billion in total industry sales, four million jobs, and $60 billion in federal, state and local government tax revenues. The states reaping the greatest economic benefits from radioactive materials are Pennsylvania, Virginia, Oregon, California, Tennessee, Minnesota and Washington.

The use of nuclear energy to produce electricity also has a significant impact on the economy. It accounts for $90 billion in total sales of goods and services, 442,000 jobs, and $17.8 billion in federal, state and local government tax revenues.

Common radioisotopes and their uses

Americium-241

Used in many smoke detectors for homes and businesses to measure levels of toxic lead in dried paint samples, to ensure uniform thickness in rolling processes like steel and paper production, and to help determine where oil wells should be drilled.

Cadmium-109

Used to analyze metal alloys for checking stock and sorting scrap.

Calcium-47

Aid to biomedical researchers studying the cell function and bone formation of mammals.

Californium-252

Used to measure the mineral content of coal ash and to measure the moisture of materials stored in silos.

Carbon-14

Used in research to ensure that potential new drugs are metabolized without forming harmful by-products.

Cesium-137

Used to treat cancers; to calibrate the equipment used to measure correct patient dosages of radioactive pharmaceuticals; to measure and control the liquid flow in oil pipelines; to tell researchers whether oil wells are plugged by sand; and to ensure the right fill level for packages of food, drugs and other products. (The products in these packages do not become radioactive.)

Chromium-51

Used in research in red blood cell survival studies.

Cobalt-57

Used in nuclear medicine to help physicians interpret diagnostic scans of patients' organs, and to diagnose pernicious anemia.

Cobalt-60

Used to sterilize surgical instruments; to improve the safety and reliability of industrial fuel oil burners; and to preserve poultry, fruits and spices.

Copper-67

When injected with monoclonal antibodies into a cancer patient, helps the antibodies bind to and destroy the tumor.

Curium-244

Used in mining to analyze material excavated from pits and slurries from drilling operations.

Iodine-123

Widely used to diagnose thyroid disorders.

Iodine-129

Used to check some radioactivity counters in in vitro diagnostic testing laboratories.

Iodine-131

Used to diagnose and treat thyroid disorders. (Former President George Bush and Mrs. Bush were both successfully treated for Grave's disease, a thyroid disease, with radioactive iodine.)

Iridium-192

Used to test the integrity of pipeline welds, boilers and aircraft parts.

Iron-55

Used to analyze electroplating solutions.

Krypton-85

Used in indicator lights in appliances like clothes washers and dryers, stereos and coffeemakers; to gauge the thickness of thin plastics, sheet metal, rubber, textiles and paper; and to measure dust and pollutant levels.

Nickel-63

Used to detect explosives and as voltage regulators and current surge protectors in electronic devices.

Phosphorus-32

Used in molecular biology and genetics research.